Transient Severe Functional Mitral Valve Regurgitation

A 79-year-old woman presented with recurrent pulmonary edema.Extensive testing spanning 5 admissions showed only mild mitral regurgitation (MR).A transthoracic echocardiogram with the patient in click here the supine position and passive leg raise showed severe MR.This suggested transient severe MR.She underwent mitral valve dea eyewear replacement

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Checkpoint inhibitor use in two heart transplant patients with metastatic melanoma and review of high-risk populations

Due to the unique side-effect profile of immune checkpoint inhibitors (ICIs), groups of patients deemed to be at high risk of complications were excluded from trials that proved the efficacy and safety of these agents in patients with various malignancies.Among these excluded patients were those with prior solid organ transplantation, chronic viral

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In vitro tissue-engineered adipose constructs for modeling disease

Abstract Adipose tissue is a vital tissue in mammals that functions to insulate our bodies, regulate our internal thermostat, protect our organs, store energy (and burn energy, in the case of beige and brown fat), and provide endocrine signals to other organs in the body.Tissue engineering of adipose and other soft tissues may prove essential for p

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